| Biggest home win | National League South 2018/19 | Eastbourne Borough | 6-0 | Dartford |
| | National League South 2007/08 | Eastbourne Borough | 6-0 | Basingstoke Town |
| | National League South 2021/22 | Eastbourne Borough | 6-0 | Braintree Town |
| Biggest away win | National League South 2007/08 | Sutton United | 1-5 | Eastbourne Borough |
| | National League South 2022/23 | Slough Town | 1-5 | Eastbourne Borough |
| | National League South 2007/08 | Fisher Athletic | 0-4 | Eastbourne Borough |
| | National League South 2005/06 | Maidenhead United | 2-6 | Eastbourne Borough |
| | National League South 2015/16 | Basingstoke Town | 1-5 | Eastbourne Borough |
| | National League South 2007/08 | Dorchester | 0-4 | Eastbourne Borough |
| | National League South 2017/18 | Poole Town | 0-4 | Eastbourne Borough |
| | National League South 2016/17 | Hemel Hempstead | 0-4 | Eastbourne Borough |
| Worst away defeat | National League South 2019/20 | Concord Rangers | 5-0 | Eastbourne Borough |
| | National League South 2005/06 | St. Albans | 5-0 | Eastbourne Borough |
| | National League South 2019/20 | Braintree Town | 5-0 | Eastbourne Borough |
| | National League South 2022/23 | Chelmsford City | 5-0 | Eastbourne Borough |
| Worst home defeat | National League South 2021/22 | Eastbourne Borough | 2-7 | Dartford |
| | National League South 2021/22 | Eastbourne Borough | 0-5 | Hampton & Richmond |
